What is kafka’s message about a global issue in the metamorphosis, and how do his creative choices contribute to the meaning of the work?

What is Kafka’s message about a global issue in The Metamorphosis, and how do his creative choices contribute to the meaning of the work?
refer to the metamorphosis book for evidence
pick the global issue of social isolation and how that is a message in the book and how does Kafka’s creative choices contribute to the meaning of his work.